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Details

Super GermiCide-Compound Sulfamonomethoxine Sodium Injection

50ml»ì¸Ð¾úÎÞµÐ.jpgComposition

Each ml contains Sulfamonomethoxine Sodium 100mg and Triethoprim 20mg as active ingredients, Sodium Thiosulphate, Edetate Disodium, Sodium hydroxide and Polyethylene Glycol-400 as excipients.


Pharmacological Properties 

Sulfamonomethoxine inhibits bacterial synthesis of dihydrofolic acid from PABA. Trimethoprim prevent dihydrofolic acid from being reduced to tetrahydrofolic acid. With combination of Sulfamonomethoxine and Trimethoprim, Super GermiCide provides dual block to tetrahydrofolic acid synthesis of bacteria from two different links, the growth and reproduction of bacteria is therefore inhibited. Moreover, the antibacterial action can be enhanced to several to hundred times, and the antimicrobial range can be enlarged, and the production of resistance strain can be reduced.

Super GermiCide can maintain high blood concentration. Solvent of Super GermiCide is slow-release delivering agent, the drug substance can maintain effective blood concentration for 24-36hs.


Indications

For the treatment of systemic, genitourinary, gastrointestinal, digestive pulmonary and respiratory infection caused by sensitive strains including bacteria and protozoan.


Target Animals

Cattle, sheep and swine.


Dosage and Administration

Administer by deep intramuscular injection.

Cattle: 0.1ml per 1kg bodyweight (10ml per 100kg bodyweight).

Sheep and Swine: 0.2ml per 1kg bodyweight (10ml per 50kg bodyweight).

Once a day for two days.


Warnings, Precautions, etc.

1. Cannot be combined with tetracycline, kanamycin, lincomycin, etc.

2. When combined with diuretics such as thiazide or furosemide, it can aggravate nephrotoxicity.

3. The combination of antacids and sulfonamides can reduce its bioavailability.

4. Some drugs containing p-aminobenzoyl, such as procaine, tetracaine, etc., can produce PABA in the body, and yeast tablets contain PABA required for bacterial metabolism, which can reduce the drug effect.

5. Caution should also be taken when used in livestock with impaired liver and renal.


Use during pregnancy and lactation

Not for pregnant livestock, or livestock producing milk for human consumption.


Withdrawal Period(s)

Meat and offal: 20 days.


Presentation

In a 50ml bottle.


Storage

Store in a cool and dry place below 30¡æ, protect from light.



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